Abdelmohsen, Hend and Copeland, Nikki and Hardy, John (2023) Light-responsive biomaterials for ocular drug delivery. Drug Delivery and Translational Research, 13 (8). pp. 2159-2182. ISSN 2190-3948
Abdelmohsen_et_al_DDTR_2022_accepted.pdf - Accepted Version
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Abstract
Light-responsive biomaterials can be used for the delivery of therapeutic drugs and nucleic acids, where the tunable/precise delivery of payload highlights the potential of such biomaterials for treating a variety of conditions. The translucency of eyes and advances of laser technology in ophthalmology make light-responsive delivery of drugs feasible. Importantly, light can be applied in a non-invasive fashion; therefore, light-triggered drug delivery systems have great potential for clinical impact. This review will examine various types of light-responsive polymers and the chemistry that underpins their application as ophthalmic drug delivery systems. Graphical abstract: [Figure not available: see fulltext.].