Oral health and all-cause, cardiovascular disease, and respiratory mortality in older people in the UK and USA

Kotronia, Eftychia and Brown, Heather and Papacosta, A. Olia and Lennon, Lucy T. and Weyant, Robert J. and Whincup, Peter H. and Wannamethee, S. Goya and Ramsay, Sheena E. (2021) Oral health and all-cause, cardiovascular disease, and respiratory mortality in older people in the UK and USA. Scientific Reports, 11 (1). ISSN 2045-2322

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Abstract

Preventing deterioration of oral health in older age can be crucial for survival. We aimed to examine associations of oral health problems with all-cause, cardiovascular disease (CVD), and respiratory mortality in older people. We used cohort data from the British Regional Health Study (BRHS) (N = 2147, 71–92 years), and the Health, Aging and Body Composition (HABC) Study (USA) (N = 3075, 71–80 years). Follow-up was 9 years (BRHS) and 15 years (HABC Study). Oral health comprised tooth loss, periodontal disease, dry mouth, and self-rated oral health. Cox regression was performed for all-cause mortality, competing risks for CVD mortality, and accelerated failure time models for respiratory mortality. In the BRHS, tooth loss was associated with all-cause mortality (hazard ratio (HR) = 1.59, 95% CI 1.09, 2.31). In the HABC Study, tooth loss, dry mouth, and having ≥ 3 oral problems were associated with all-cause mortality; periodontal disease was associated with increased CVD mortality (subdistribution hazard ratio (SHR) = 1.49, 95% CI 1.01, 2.20); tooth loss, and accumulation of oral problems were associated with high respiratory mortality (tooth loss, time ratio (TR) = 0.73, 95% CI 0.54, 0.98). Findings suggest that poor oral health is associated with mortality. Results highlight the importance of improving oral health to lengthen survival in older age.

Item Type:
Journal Article
Journal or Publication Title:
Scientific Reports
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1000
Subjects:
ID Code:
169422
Deposited By:
Deposited On:
03 May 2022 14:25
Refereed?:
Yes
Published?:
Published
Last Modified:
03 May 2022 14:25