ICTV Virus Taxonomy Profile:Herpesviridae 2021

Gatherer, Derek and Depledge, Daniel P and Hartley, Carol A and Szpara, Moriah L and Vaz, Paola K and Benkő, Mária and Brandt, Curtis R and Bryant, Neil A and Dastjerdi, Akbar and Doszpoly, Andor and Gompels, Ursula A and Inoue, Naoki and Jarosinski, Keith W and Kaul, Rajeev and Lacoste, Vincent and Norberg, Peter and Origgi, Francesco C and Orton, Richard J and Pellett, Philip E and Schmid, D Scott and Spatz, Stephen J and Stewart, James P and Trimpert, Jakob and Waltzek, Thomas B and Davison, Andrew J (2021) ICTV Virus Taxonomy Profile:Herpesviridae 2021. Journal of General Virology, 102 (10). ISSN 0022-1317

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Abstract

Members of the family Herpesviridae have enveloped, spherical virions with characteristic complex structures consisting of symmetrical and non-symmetrical components. The linear, double-stranded DNA genomes of 125-241 kbp contain 70-170 genes, of which 43 have been inherited from an ancestral herpesvirus. In general, herpesviruses have coevolved with and are highly adapted to their hosts, which comprise many mammalian, avian and reptilian species. Following primary infection, they are able to establish lifelong latent infection, during which there is limited viral gene expression. Severe disease is usually observed only in the foetus, the very young, the immunocompromised or following infection of an alternative host. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Herpesviridae, which is available at ictv.global/report/herpesviridae.

Item Type:
Journal Article
Journal or Publication Title:
Journal of General Virology
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2400/2406
Subjects:
ID Code:
161620
Deposited By:
Deposited On:
29 Oct 2021 11:50
Refereed?:
Yes
Published?:
Published
Last Modified:
27 Nov 2021 06:09