Escherichia coli as an antibody expression host for the production of diagnostic proteins: significance and expression

Huleani, S. and Roberts, M.R. and Beales, L. and Papaioannou, E.H. (2022) Escherichia coli as an antibody expression host for the production of diagnostic proteins: significance and expression. Critical Reviews in Biotechnology, 42 (5). pp. 756-773. ISSN 0738-8551

Abstract

This review article concerns the production of recombinant antibody fragments for applications mainly in the diagnostic sector. The so-called “point of care diagnostics” is very important for timely diagnosis and treatment, thus being able to save lives and resources. There is intense pressure for more accurate and less expensive rapid diagnostic tests, with a value preferably