Brønsted Acid Catalyzed Peterson Olefinations

Britten, Thomas K. and McLaughlin, Mark G. (2020) Brønsted Acid Catalyzed Peterson Olefinations. The Journal of Organic Chemistry, 85 (2). pp. 301-305.

Abstract

A mild and facile Peterson olefination has been developed employing low catalyst loading of the Brønsted acid HNTf2. The reactions are typically performed at room temperature, with the reaction tolerant to a range of useful functionalities. Furthermore, we have extended this methodology to the synthesis of enynes.