Strategic testing approaches for targeted disease monitoring can be used to inform pandemic decision-making

Nichols, J.D. and Bogich, T.L. and Howerton, E. and Bjørnstad, O.N. and Borchering, R.K. and Ferrari, M. and Haran, M. and Jewell, C. and Pepin, K.M. and Probert, W.J.M. and Pulliam, J.R.C. and Runge, M.C. and Tildesley, M. and Viboud, C. and Shea, K. (2021) Strategic testing approaches for targeted disease monitoring can be used to inform pandemic decision-making. Plos Biology, 19 (6). ISSN 1544-9173

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Abstract

More than 1.6 million Servere Acute Respiratory Syndrome Cronovirus 2(SARS-COV-2)tests were administered daily in the United States at the peak of the epidemic, with a significant focus on individual treatment. Here, we show that objective-driven, strategic sampling designs and analyses can maximize information gain at the population level, which is necessary to increase situational awareness and predict, prepare for, and respond to a pandemic, while also continuing to inform individual treatment. By focusing on specific objectives such as individual treatment or disease prediction and control (e.g., via the collection of population- level statistics to inform lockdown measures or vaccine rollout) and drawing from the literature on capture-recapture methods to deal with nonrandom sampling and testing errors, we illustrate how public health objectives can be achieved even with limited test availability when testing programs are designed a priori to meet those objectives. © 2021 Public Library of Science. All rights reserved.

Item Type:
Journal Article
Journal or Publication Title:
Plos Biology
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2400
Subjects:
ID Code:
157199
Deposited By:
Deposited On:
30 Jul 2021 09:55
Refereed?:
Yes
Published?:
Published
Last Modified:
20 Oct 2021 06:08