Elimination of STH morbidity in Zimbabwe : Results of 6 years of deworming intervention for school-age children

Midzi, N. and Montresor, A. and Mutsaka-Makuvaza, M.J. and Fronterre, C. and Manangazira, P. and Phiri, I. and Johnson, O. and Mhlanga, G. and Diggle, P.J. (2020) Elimination of STH morbidity in Zimbabwe : Results of 6 years of deworming intervention for school-age children. PLoS Neglected Tropical Diseases, 14 (10): e0008739. pp. 1-12. ISSN 1935-2727

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This paper reports the prevalence and intensity of soil-transmitted helminth (STH) infections measured in Zimbabwe before and after a control intervention based on annual deworming of school-age children (SAC) conducted from 2012 to 2018. In 2010, epidemiological data were collected from 13 195 SAC in 255 randomly selected schools in all districts nationwide using, as diagnostic methods, the Kato–Katz and the formal ether stool concentration technique. At follow up, conducted in 2017, only Kato–Katz was performed; specimens were collected from 13 352 children in 336 schools. The data were evaluated using a geospatial approach. The national prevalence of STH infection in SAC was estimated at 5.8% at baseline, with 0.8% of infections of moderate and heavy intensity. Preventive chemotherapy (PC) targeted all 2.5 million children of school age enrolled in Zimbabwe, with coverage ranging from 49% to 85%. At follow up, national prevalence of STH in SAC was estimated at 0.8%; infections of moderate and heavy intensity almost disappeared (0.1% prevalence). As a result, Zimbabwe can suspend deworming activities in 54 districts and reduce the frequency of PC in the remaining six districts. The total amount of albendazole tablets needed will be approximately 100 000 a year. © 2020 Midzi et al.

Item Type:
Journal Article
Journal or Publication Title:
PLoS Neglected Tropical Diseases
Uncontrolled Keywords:
?? infectious diseasespublic health, environmental and occupational healthpharmacology, toxicology and pharmaceutics(all) ??
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Deposited On:
18 Nov 2020 17:20
Last Modified:
15 Jul 2024 21:12