An amide hydrogen bond templated [1]rotaxane displaying a peptide motif - demonstrating an expedient route to synthetic mimics of lasso peptides

Young, Matthew John and Akien, Geoffrey and Evans, Nicholas (2020) An amide hydrogen bond templated [1]rotaxane displaying a peptide motif - demonstrating an expedient route to synthetic mimics of lasso peptides. Organic and Biomolecular Chemistry, 18 (27). pp. 5203-5209. ISSN 1477-0520

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Abstract

The rapid synthesis of an amide hydrogen bond templated [1]rotaxane is reported - demonstrating a potential pathway to synthetic analogues of lasso peptides. The structures of the [1]rotaxane and its unthreaded isomer have been characterized by NMR spectroscopy and modelled using DFT calculations.

Item Type:
Journal Article
Journal or Publication Title:
Organic and Biomolecular Chemistry
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1600/1606
Subjects:
ID Code:
145072
Deposited By:
Deposited On:
24 Jun 2020 11:05
Refereed?:
Yes
Published?:
Published
Last Modified:
01 Oct 2020 03:50