Is cognitive behavioural therapy effective for individuals experiencing thought disorder?

Shryane, Nick and Drake, Richard and Morrison, Anthony P. and Palmier-Claus, Jasper (2020) Is cognitive behavioural therapy effective for individuals experiencing thought disorder? Psychiatry Research, 285: 112806. ISSN 0165-1781

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Various clinical guidelines recommend cognitive behavioural therapy (CBT) to treat psychosis without reference to patients’ thought disorder. However, there is a risk that disorganized thinking hampers CBT. We tested the prediction that thought disorder would interfere with the effectiveness of CBT for hallucinations and delusions, compared to treatment as usual and supportive counselling, in secondary data from two large, single blind randomised controlled trials. We fitted latent growth curve models separately for the development of frequency and distress of symptoms. CBT was significantly more successful than counselling in reducing delusional frequency in the short term and hallucinatory distress at any point, even in those with relatively high thought disorder. We found little evidence that clinicians should restrict CBT in this subgroup of patients. Nevertheless, the findings highlight the importance of effective initial treatment of thought disorder in maximising the benefit of CBT for psychosis, particularly for reducing distress from hallucinations.

Item Type:
Journal Article
Journal or Publication Title:
Psychiatry Research
Additional Information:
This is the author’s version of a work that was accepted for publication in Psychiatry Research. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Psychiatry Research, 285, 2020 DOI: 10.1016/j.psychres.2020.112806
Uncontrolled Keywords:
?? psychosiscognitive behavioural therapythought disorderrandomized controlled trialpsychiatry and mental healthbiological psychiatry ??
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Deposited On:
28 Jan 2020 13:45
Last Modified:
28 Nov 2023 11:33