Optimizing Nanohydroxyapatite Nanocomposites for Bone Tissue Engineering

Lowe, B. and Hardy, J.G. and Walsh, L.J. (2019) Optimizing Nanohydroxyapatite Nanocomposites for Bone Tissue Engineering. ACS Omega. ISSN 2470-1343

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Abstract

Bone tissue engineering involves the combined use of materials with functional properties to regenerate bone. Nanohydroxyapatite (nHA) can influence the behavior of cells. The functional and structural properties of nHA can be controlled during nanoparticle synthesis. This review defines the relationship between the attributes of nHA nanoparticles and their biological effects, focusing on biocompatibility, surface-area-to-volume ratio, bonding chemistry, and substrate functionality. The paper explores how these aspects have been applied in the development of scaffolds for the repair of damaged bone or regeneration of missing bone.

Item Type:
Journal Article
Journal or Publication Title:
ACS Omega
ID Code:
140068
Deposited By:
Deposited On:
13 Jan 2020 09:10
Refereed?:
Yes
Published?:
Published
Last Modified:
01 Dec 2020 07:46