A congener specific method for the analysis of polychlorinated biphenyls (PCBs) in human milk

Duarte-Davidson, R. and Burnett, V. and Waterhouse, K. S. and Jones, K. C. (1991) A congener specific method for the analysis of polychlorinated biphenyls (PCBs) in human milk. Chemosphere, 23 (2). pp. 119-131. ISSN 0045-6535

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Abstract

A method for the congener specific analysis of PCBs in human milk is described. This involves solvent extraction, acid digestion, clean-up by column chromatography and quantification by HRGC with electron capture detection and confirmation by MSD. Over 50 congeners, selected because of their reported toxicity and abundance in environmental and biological samples, are determined. Results from the analysis of UK samples of milk are presented and indicate that the mixture of congeners between different milk samples is very similar. PCB IUPAC numbers 138, 153 and 180 were the most abundant congeners, each accounting for >10% of the total PCB content of milk, while 15, 18, 28, 52, 66, 61 74, 99, 101, 105, 118, 187, 156 202 and 170 each constituted between 2 and 10%. Traces (<2%) of many of the other congeners analysed (i.e. 44, 77 110, 82 151, 119, 128, 149, 183, 188 and 201) were also found. Other congeners were either not detected (<0.5%) (eg. congeners 40, 155, 169, 185, 189 and 198), or gave erratic results (eg 30, 37, 54, 104).

Item Type:
Journal Article
Journal or Publication Title:
Chemosphere
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2300/2307
Subjects:
ID Code:
137823
Deposited By:
Deposited On:
15 Oct 2019 15:20
Refereed?:
Yes
Published?:
Published
Last Modified:
01 Jan 2020 12:18