Tetranuclear Zn2Ln2 coordination clusters as catalysts in the Petasis borono-Mannich multicomponent reaction

Kumar, Prashant and Griffiths, Kieran and Lymperopoulou, Smaragda and Kostakis, George E. (2016) Tetranuclear Zn2Ln2 coordination clusters as catalysts in the Petasis borono-Mannich multicomponent reaction. RSC Advances, 6 (82). pp. 79180-79184. ISSN 2046-2069

Abstract

We report herein for the first time the efficiency of heteronuclear Zn/Ln coordination clusters (CCs) as catalysts for the multicomponent Mannich-type condensation that involves amines, aldehydes and boronic acids, known as the Petasis borono-Mannich (RBR) reaction. The reaction proceeds in very good to excellent yields (84-98%, 17 products) at room temperature with catalyst loadings as low as 1.0 mol%.