Assessing the environmental performance of NADH regeneration methods:A cleaner process using recyclable Pt/Fe3O4 and hydrogen

Saba, Tony and Burnett, Joseph W.H. and Li, Jianwei and Wang, Xiaonan and Anderson, James A. and Kechagiopoulos, Panagiotis N. and Wang, Xiaodong (2020) Assessing the environmental performance of NADH regeneration methods:A cleaner process using recyclable Pt/Fe3O4 and hydrogen. Catalysis Today, 339. 281–288. ISSN 0920-5861

Full text not available from this repository.

Abstract

Cofactor (reduced) Nicotinamide Adenine Dinucleotide (NAD(P)H) is an energy carrier in enzymatic redox reactions that are employed for the synthesis of valuable chemicals and pharmaceuticals. The high cost of NAD(P) H makes it impractical to use in stoichiometric amounts in industrial processes. This has led to the development of a variety of methods for NAD(P)H regeneration. In this work, process cleanliness of the current NADH recycling systems was evaluated using E-factor (kg(waste)/kg(NADH)) as a green chemistry metric. The E-factor obtained, depending on the process method, reaches values higher than 20000, where non-recyclable agents, including sacrificial hydride/electron donors, catalysts and electron mediators, alongside by-products (from cosubstrates), account for the overall waste. A promising alternative methodology for NADH regeneration using H-2 and recyclable Pt/Fe3O4 is presented and characterisation performed by temperature-programmed reduction (TPR), nitrogen adsorption (surface area/porosity), powder X-ray diffraction (XRD) and transmission electron microscopy (TEM) is used to elucidate the observed performance. The Pt/Fe3O4 system at room temperature delivers a turnover frequency of 20 h(-1) and the catalyst can be recycled for reuse, producing a significantly low level of waste (E-factor = similar to 1).

Item Type:
Journal Article
Journal or Publication Title:
Catalysis Today
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1500/1503
Subjects:
ID Code:
136856
Deposited By:
Deposited On:
27 Sep 2019 13:25
Refereed?:
Yes
Published?:
Published
Last Modified:
29 Apr 2020 08:20