Emerging ethical perspectives in the clustered regularly interspaced short palindromic repeats genome-editing debate.

Camporesi, Silvia and Cavaliere, Giulia (2016) Emerging ethical perspectives in the clustered regularly interspaced short palindromic repeats genome-editing debate. Personalized Medicine, 13 (6). pp. 575-586. ISSN 1741-0541

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Abstract

This paper provides an overview of the ethical issues in the international clustered regularly interspaced short palindromic repeats (CRISPR) genome editing debate from March 2015 to September 2016. We present the regulatory framework for embryo research in the UK, and explain why CRISPR is not a significant break with the past. We discuss the ethical issues arising from CRISPR applications beyond human embryos, namely the use of gene drive-engineered mosquitoes to eradicate diseases, engineering nonhuman animals to harvest organs for human transplant and engineering crops. We discuss the experiments that have demonstrated the technical feasibility of cultivating embryos in vitro for up to 14 days, and possibly beyond this limit, and the ethical issues arising from the proposal to extend the limit beyond 14 days.

Item Type:
Journal Article
Journal or Publication Title:
Personalized Medicine
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2700
Subjects:
ID Code:
136601
Deposited By:
Deposited On:
09 Sep 2019 13:15
Refereed?:
Yes
Published?:
Published
Last Modified:
01 Apr 2020 07:35