Biomimetic spinning of recombinant silk proteins

Keerl, David and Hardy, John G. and Scheibel, Thomas (2011) Biomimetic spinning of recombinant silk proteins. In: Micro- and Nanoscale Processing of Biomaterials :. Materials Research Society Symposium Proceedings, 1239 . Materials Research Society, USA, pp. 93-97. ISBN 9781605112121

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Abstract

In the past, we have successfully designed and produced a variety of engineered spider silk-like proteins (eADF3 and eADF4) based upon the primary sequence of the natural dragline proteins ADF3 and ADF4 from the spider Araneus diadematus [1]. Genetically engineered spider silk proteins can be modified at the molecular level to optimize the biochemical and mechanical properties of the final product. Although engineered spider silk proteins can be processed into fibers using different spinning methods, our group is interested in the technical realization of a biomimetic approach. Here, we present an overview over our biomimetic fiber production process.