Cardiorespiratory fitness as a predictor of short-term and lifetime estimated cardiovascular disease risk:Normative fitness thresholds and CVD risk

Swainson, Michelle and Ingle, Lee and Carroll, Sean (2019) Cardiorespiratory fitness as a predictor of short-term and lifetime estimated cardiovascular disease risk:Normative fitness thresholds and CVD risk. Scandinavian Journal of Medicine and Science in Sports, 29 (9). pp. 1402-1413.

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Abstract

Development of cardiovascular disease (CVD) remains a public health concern for young-to-middle-aged adults, now exacerbated by the increasing prevalence of obesity and sedentary lifestyles. Cardiorespiratory fitness (CRF) improves the reclassification of short-term (10-year) CVD risk, but has not been uniformly defined across studies. This study evaluated cross-sectional differences in short-term and lifetime CVD risk scores, across both absolute metabolic equivalent (MET), sex- and age-standardised CRF categories in 805 healthy apparently healthy young-to-middle aged adults (68% male; 47.4 ± 7.2 years). CVD risk factors were evaluated, and estimated cardiorespiratory fitness (CRF) measurements (METS and peak VO2) were derived from a submaximal Bruce treadmill test. CRF measures also included post-exercise heart rate recovery (HRR) data. Consistent trends showing more favorable risk factor profiles and lower short-term CVD (QRISK2), and CVD mortality (SCORE) scores, associated with higher levels of CRF were evident in both sexes. Lifetime CVD risk (Q-Lifetime) was highest in the lowest CRF categories. Peak VO2 and HRR following submaximal exercise testing contributed to the variability in short-term and lifetime CVD risk. Global CVD risk predictions were examined across different contemporary CRF classifications with inconsistent findings. Recommended absolute MET and sex- and age-standardised CRF categories were significantly associated with both short-term and lifetime risk of CVD outcomes. However, compared to internationally-derived normative CRF standards, cohort-specific CRF categories resulted in markedly different proportion of individuals classified in the “poor” CRF category at higher CVD risk.

Item Type:
Journal Article
Journal or Publication Title:
Scandinavian Journal of Medicine and Science in Sports
Additional Information:
This is the peer reviewed version of the following article: Swainson, MG, Ingle, L, Carroll, S. Cardiorespiratory fitness as a predictor of short‐term and lifetime estimated cardiovascular disease risk. Scandinavian Journal of Medicine and Science in Sports. doi: 10.1111/sms.13468 which has been published in final form at https://onlinelibrary.wiley.com/doi/full/10.1111/sms.13468 This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/3600/3612
Subjects:
ID Code:
133748
Deposited By:
Deposited On:
14 May 2019 07:55
Refereed?:
Yes
Published?:
Published
Last Modified:
19 Sep 2020 05:53