Raman spectroscopy of natural bone and synthetic apatites

Khan, A.F. and Awais, M. and Khan, A.S. and Tabassum, S. and Chaudhry, A.A. and Rehman, I.U. (2013) Raman spectroscopy of natural bone and synthetic apatites. APPLIED SPECTROSCOPY REVIEWS, 48 (4). pp. 329-355. ISSN 0570-4928

Full text not available from this repository.

Abstract

Raman spectroscopy of natural bones and hydroxyapatites is described. In addition, how Raman spectroscopy has proved crucial in providing baseline data for the modification of synthetic apatite powders that are routinely used now as bone replacement materials is explained. It is important to understand the chemical structural properties of natural bone. Bone consists of two primary components: an inorganic or mineral phase, which is mainly a carbonated form of a nanoscale crystalline calcium phosphate, closely resembling hydroxyapatite, and an organic phase, which is composed largely of type I collagen fibers. Other constituents of bone tissue include water and organic molecules such as glycosaminoglycans, glycoproteins, lipids, and peptides. Ions such as sodium, magnesium, fluoride, and citrate are also present, as well as hydrogenophosphate. Hence, the mineral phase in bone may be characterized essentially as nonstoichiometric substituted apatite. Such a distinction is important in the development of synthetic calcium phosphates for application as skeletal implants. An understanding of bone function and its interfacial relationship to an implant clearly depends on the associated structure and composition. Therefore, it is essential to fully understand the chemical composition of bone, and Raman spectroscopy is an excellent technique for such an analysis. © 2013 Taylor and Francis Group, LLC.

Item Type:
Journal Article
Journal or Publication Title:
APPLIED SPECTROSCOPY REVIEWS
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/1600/1607
Subjects:
ID Code:
132937
Deposited By:
Deposited On:
17 Apr 2019 08:45
Refereed?:
Yes
Published?:
Published
Last Modified:
06 May 2020 06:58