Influence of processing parameters and solid concentration on microstructural properties of gel-casted porous hydroxyapatite

Asif, A. and Nazir, R. and Riaz, T. and Ashraf, N. and Zahid, S. and Shahid, R. and Ur-Rehman, A. and Chaudhry, A.A. and Ur Rehman, I. (2014) Influence of processing parameters and solid concentration on microstructural properties of gel-casted porous hydroxyapatite. Journal of Porous Materials, 21 (1). pp. 31-37. ISSN 1380-2224

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Abstract

Porous hydroxyapatite (HA) scaffolds with interconnected porosity have been successfully fabricated by using food grade gelatin as a gelling agent. Phase stability, chemical composition and topographical features of HA scaffolds were evaluated by X-ray diffraction (XRD), Fourier transform infrared spectroscopy and scanning electron microscopy respectively. XRD study revealed that additives used in the gel-casting process did not influence the phase composition of the investigated materials. The porosity of sintered scaffolds was assessed by the liquid displacement method and found to be 55-76 %. The pores were tailored to spherical shape and size in the range 300-400 nm, feature of utmost interest to clinicians for cell attachment, proliferation and development of soft tissues. Biocompatibility of HA scaffolds was evaluated via hemolysis studies. The results of hemolysis proved the highly biocompatible behavior of the synthesized HA scaffolds. © 2013 Springer Science+Business Media New York.

Item Type:
Journal Article
Journal or Publication Title:
Journal of Porous Materials
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2200/2210
Subjects:
?? BIOCOMPATIBILITYGEL-CASTINGHYDROXYAPATITEINTERCONNECTED POROSITYPOROUS SCAFFOLDSCHEMICAL COMPOSITIONSMICRO-STRUCTURAL PROPERTIESPOROUS HYDROXYAPATITEPOROUS SCAFFOLDPROCESSING PARAMETERSTOPOGRAPHICAL FEATURESBLOODCASTINGFOURIER TRANSFORM INFRARED SPECTROSC ??
ID Code:
132926
Deposited By:
Deposited On:
17 Apr 2019 09:25
Refereed?:
Yes
Published?:
Published
Last Modified:
21 Sep 2023 02:36