Synthesis and characterization of grafted nanohydroxyapatites using functionalized surface agents

Haque, S. and Rehman, I. and Darr, J.A. (2007) Synthesis and characterization of grafted nanohydroxyapatites using functionalized surface agents. Langmuir, 23 (12). pp. 6671-6676. ISSN 0743-7463

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Abstract

Synthetic hydroxyapatite, HA [Ca10(PO4) 6(OH)2], is a bioactive material that is chemically similar to biological apatite, the mineral phase of bone (a nanocomposite material). Synthetic biocomposites, comprising a polymer and hydroxyapatite that are used for bone replacement, have limitations when loaded under fatigue in that the weak mechanical bond between the two phases can result in failure at the interface. Chemical coupling of the HA and polymer matrix may provide a means of improving the interfacial bonding between the polymer and HA phases. Herein, we report our first steps toward developing chemically coupled nano-biocomposites via a two-step process. We describe the synthesis and characterization of surface-grafted hydroxyapatite (SG-HA), which possesses a reactive C=C functional group. In future work, we will report on the second step, namely the coupling of this functional group to a polymer by a copolymerization reaction to give a chemically coupled nano-biocomposite. The SG-HA reported herein was characterized by a range of methods including 31P and 13C magic-angle spinning (MAS)-NMR, Fourier transform infrared (FTIR), and Raman spectroscopy. © 2007 American Chemical Society.

Item Type:
Journal Article
Journal or Publication Title:
Langmuir
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/3100/3104
Subjects:
ID Code:
132862
Deposited By:
Deposited On:
16 Apr 2019 15:05
Refereed?:
Yes
Published?:
Published
Last Modified:
09 Sep 2020 05:55