Applications of Raman spectroscopy in dentistry part II:Soft tissue analysis

Ramakrishnaiah, R. and Kotha, S.B. and Alkheraif, A.A. and Celur, S.L. and Divakar, D.D. and Javed, F. and Rehman, I.U. (2016) Applications of Raman spectroscopy in dentistry part II:Soft tissue analysis. APPLIED SPECTROSCOPY REVIEWS, 51 (10). pp. 799-821. ISSN 0570-4928

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Raman spectroscopy is rapidly moving from an experimental technique for the analysis of biological molecules to a tool for the real-time clinical diagnosis and in situ evaluation of the oral tissue in medical and dental research. The purpose of this study is to identify various applications of Raman spectroscopy, to evaluate the contemporary status, and to explore future directions in the field of dentistry. Several in-depth applications are presented to illustrate Raman spectroscopy in early diagnosis of soft tissue abnormalities. Raman spectroscopy allows researchers to analyze histological and biochemical composition of biological tissues. The technique not only demonstrates its role in the disclosure of dysplasia and malignancy, but also in performing guided biopsies, diagnosing sialoliths, and assessment of surgical margins. Raman spectroscopy is used to identify the molecular structures and their components to give substantial information about the chemical structure properties of these molecules. In this article, we acquaint the utilization of Raman spectroscopy in analyzing the soft tissues in relation to dentistry.

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16 Apr 2019 09:15
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20 Sep 2023 01:22