FTIR analysis of natural and synthetic collagen

Riaz, Tehseen and Zeeshan, Rabia and Zarif, Faiza and Ilyas, Kanwal and Muhammad, Nawshad and Safi, Sher Zaman and Rahim, Abdur and Rizvi, Syed A. A. and Rehman, Ihtesham Ur (2018) FTIR analysis of natural and synthetic collagen. APPLIED SPECTROSCOPY REVIEWS, 53 (9). pp. 703-746. ISSN 0570-4928

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Abstract

Collagen is the most abundant protein in humans and animals, comprising of one third of the total proteins that accounts for three quarters of the dry weight skin in humans. Collagen containing a range of proteins has been reported for tissue engineering applications, but, only a small number of studies related to chemical structure evaluation of collagen are found in the literature. Collagen can be obtained from both the natural and synthetic sources and offers a wide range of biomedical applications due to its excellent biocompatibility and low immunogenicity. Hence, it is important to identify chemical structural properties of collagen and Fourier transform infrared (FTIR) appears to be a technique of choice to study their chemical structure. This review aims to highlight the use of FTIR to study collagen-based biomaterials, using it for characterization of collagen extracted from various sources. Characterization of collagen-based materials used in wound healing, skin substitutes, derma fillers, and aging of skin, collagen containing drug delivery agents, collagen-based materials used in tissue engineering, bone regeneration, and osteogenic differentiation is discussed in detail. FTIR analysis of collagen-containing materials used for dental applications, cleft-palate, and in alveolar-ridge preservation has also been highlighted.

Item Type:
Journal Article
Journal or Publication Title:
APPLIED SPECTROSCOPY REVIEWS
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/3100/3105
Subjects:
?? ftircollagenmolecular structurecharacterizationbiomedical materialsinstrumentationspectroscopy ??
ID Code:
132722
Deposited By:
Deposited On:
12 Apr 2019 13:00
Refereed?:
Yes
Published?:
Published
Last Modified:
15 Jul 2024 19:15