Should the 14‐day rule for embryo research become the 28‐day rule?

Appleby, John B and Bredenoord, Annelien L (2018) Should the 14‐day rule for embryo research become the 28‐day rule? EMBO Molecular Medicine. ISSN 1757-4676

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Abstract

The “14‐day rule”—broadly construed—is used in science policy and regulation to limit research on human embryos to a maximum period of 14 days after their creation or to the equivalent stage of development that is normally attributed to a 14‐day‐old embryo (Hyun et al, 2016; Nuffield Council on Bioethics, 2017). For several decades, the 14‐day rule has been a shining example of how science policy and regulation can be developed with interdisciplinary consensus and applied across a number of countries to help fulfil an ethical and practical purpose: to facilitate efficient and ethical embryo research. However, advances in embryology and biomedical research have led to suggestions that the 14‐day rule is no longer adequate (Deglincerti et al, 2016; Shahbazi et al, 2016; Hurlbut et al, 2017). Therefore, should the 14‐day rule be extended and, if so, where should we draw a new line for permissible embryo research? Here, we provide scientific, regulatory and ethical arguments that the 14‐day rule should be extended to 28 days (or the developmental equivalent stage of a 28‐day‐old embryo).

Item Type: Journal Article
Journal or Publication Title: EMBO Molecular Medicine
Uncontrolled Keywords: /dk/atira/pure/subjectarea/asjc/1300/1313
Subjects:
Departments: Faculty of Health and Medicine > Medicine
ID Code: 126824
Deposited By: ep_importer_pure
Deposited On: 10 Aug 2018 13:02
Refereed?: No
Published?: Published
Last Modified: 21 Feb 2020 04:18
URI: https://eprints.lancs.ac.uk/id/eprint/126824

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