Items where Department is "Faculty of Health and Medicine > Biomedical & Life Sciences" and Year is 2012
Number of items: 48.
Abdelwahab, Nuha Z. and Crossman, Arthur T. and Sullivan, Lauren and Ferguson, Michael A J and Urbaniak, Mick (2012) Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness. Chemical Biology and Drug Design, 79 (3). pp. 270-278. ISSN 1747-0277
Ahmadzai, Abdullah A. and Trevisan, Julio and Fullwood, Nigel J. and Carmichael, Paul L. and Scott, Andrew D. and Martin, Francis L. (2012) The Syrian hamster embryo (SHE) assay (pH 6.7): mechanisms of cell transformation and application of vibrational spectroscopy to objectively score endpoint alterations. Mutagenesis, 27 (3). pp. 257-266. ISSN 0267-8357
Ahmadzai, Abdullah A. and Trevisan, Julio and Pang, Weiyi and Patel, Imran I. and Fullwood, Nigel J. and Bruce, Shannon W. and Pant, Kamala and Carmichael, Paul L. and Scott, Andrew D. and Martin, Francis L. (2012) Classification of test agent-specific effects in the Syrian hamster embryo assay (pH 6.7) using infrared spectroscopy with computational analysis. Mutagenesis, 27 (3). pp. 375-382. ISSN 0267-8357
Alhamoruni, A. and Wright, Karen and Larvin, M. and O'Sullivan, S. E. (2012) Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability. British Journal of Pharmacology, 165 (8). pp. 2598-610. ISSN 1476-5381
Angus, Allan G. N. and Loquet, Antoine and Stack, Séamus J. and Dalrymple, David and Gatherer, Derek and Penin, François and Patel, Arvind H. (2012) Conserved glycine 33 residue in flexible domain I of hepatitis C virus core protein is critical for virus infectivity. Journal of Virology, 86 (2). pp. 679-690. ISSN 0022-538X
Austin, Zoe and Alcock, Ruth and Christley, Robert and Haygarth, Philip and Heathwaite, Louise and Latham, Sophia and Mort, Margaret and Oliver, David and Pickup, Roger and Wastling, Jonathan M. and Wynne, Brian (2012) Policy, practice and decision making for zoonotic disease management:water and cryptosporidium. Environment International, 40 (n/a). pp. 70-78. ISSN 0160-4120
Bernjak, Alan and Stefanovska, Aneta and McClintock, Peter V. E. and Owen-Lynch, P. Jane and Clarkson, Peter B. M. (2012) Coherence between fluctuations in blood flow and oxygen saturation. Fluctuation and Noise Letters, 11 (1). -. ISSN 0219-4775
Blagrove, Marcus S. C. and Arias-Goeta, Camilo and Failloux, Ana-Bella and Sinkins, Steven (2012) Wolbachia strain wMel induces cytoplasmic incompatibility and blocks dengue transmission in Aedes albopictus. Proceedings of the National Academy of Sciences, 109 (1). pp. 255-260. ISSN 0027-8424
Bomfim, Theresa R. and Forny-Germano, Leticia and Sathler, Luciana B. and Brito-Moreira, Jordano and Houzel, Jean-Christophe and Decker, Helena and Silverman, Michael A. and Kazi, Hala and Melo, Helen M. and McClean, Paula L. and Holscher, Christian and Arnold, Steven E. and Talbot, Konrad and Klein, William L. and Munoz, Douglas P. and Ferreira, Sergio T. and De Felice, Fernanda G. (2012) An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers. Journal of Clinical Investigation, 122 (4). pp. 1339-1353. ISSN 1558-8238
Camus, M. Florencia and Clancy, David J. and Dowling, Damian K. (2012) Mitochondria, maternal inheritance, and male aging. Current Biology, 22 (18). pp. 1717-1721. ISSN 0960-9822
Dawson, Neil and Thompson, Rhiannon J. and McVie, Allan and Thomson, David M. and Morris, Brian J. and Pratt, Judith A. (2012) Modafinil reverses phencyclidine-induced deficits in cognitive flexibility, cerebral metabolism and functional brain connectivity. Schizophrenia Bulletin, 38 (3). pp. 457-474. ISSN 0586-7614
Diaz-Albiter, Hector and Sant'anna, Mauricio R V and Genta, Fernando A and Dillon, Rod J (2012) Reactive Oxygen Species-mediated Immunity against Leishmania mexicana and Serratia marcescens in the Phlebotomine Sand Fly Lutzomyia longipalpis. Journal of Biological Chemistry, 287 (28). pp. 23995-24003. ISSN 0021-9258
Faivre, Emilie and Hamilton, Alison and Hölscher, Christian (2012) Effects of acute and chronic administration of GIP analogues on cognition, synaptic plasticity and neurogenesis in mice. European Journal of Pharmacology, 674 (2-3). pp. 294-306. ISSN 0014-2999
Foulds, Penny and Mann, David and Allsop, David (2012) Phosphorylated α-synuclein as a potential biomarker for Parkinson's disease (Editorial). Expert Review of Molecular Diagnostics, 12 (2). pp. 115-117. ISSN 1473-7159
Foulds, Penny and Yokota, O and Thurston, A and Davidson, Y and Ahmed, Z and Holton, J and Thompson, J C and Akiyama, H and Arai, T and Hasegawa, M and Gerhard, A and Allsop, David and Mann, D M A (2012) Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies. Neurobiology of disease, 45 (1). pp. 188-195. ISSN 1095-953X
Gao, Chong and Hölscher, Christian and Liu, Yueze and Li, Lin (2012) GSK3:a key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease. Reviews in the Neurosciences, 23 (1). pp. 1-11. ISSN 0334-1763
Gengler, Simon and McClean, Paula L. and McCurtin, Ruth and Gault, Victor A. and Holscher, Christian (2012) Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice. Neurobiology of Aging, 33 (2). pp. 265-276. ISSN 0197-4580
Ginger, Michael and Sam, Katharine A. and Allen, James W. A. (2012) Probing why trypanosomes assemble atypical cytochrome c with an AxxCH haem-binding motif instead of CxxCH. Biochemical Journal, 448 (2). pp. 253-260. ISSN 0264-6021
Ginger, Michael L. and McKean, Paul G. and Burchmore, Richard and Grant, Karen M. (2012) Proteomic insights into parasite biology. Parasitology, 139 (9). pp. 1101-1102. ISSN 0031-1820
Greaves, Erin A. and Copeland, Nikki A. and Coverley, Dawn and Ainscough, Justin F. X. (2012) Cancer-associated variant expression and interaction of CIZ1 with cyclin A1 in differentiating male germ cells. Journal of Cell Science, 125. pp. 2466-2477.
Grishin, Ilja and Tinker, Claire and Allsop, David and Robson, Alex and Kolosov, Oleg (2012) Nanoscale SPM characterisation of nacre aragonite plates and synthetic human amyloid fibres. In: NSTI-Nanotech 2012. CRC PRESS-TAYLOR & FRANCIS GROUP, Santa Clara, USA, pp. 110-113. ISBN 9781466562745
Hamilton, Alison and Holscher, Christian (2012) The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease. Brain Research, 1449. pp. 83-93. ISSN 0006-8993
Holscher, Christian (2012) Potential roles of glucagon-like peptide-1 (GLP-1) in neuroprotection. CNS Drugs, 26 (10). pp. 871-882. ISSN 1179-1934
Horst, Daniëlle and Burrows, Scott R. and Gatherer, Derek and van Wilgenburg, Bonnie and Boer, Ingrid G. J. and Bell, Melissa J. and Ressing, Maaike E. and Wiertz, Emmanuel J. H. J. (2012) Epstein-Barr virus isolates retain their capacity to evade T cell immunity through BNLF2a despite extensive sequence variation. Journal of Virology, 86 (1). pp. 572-577. ISSN 0022-538X
Hunter, Kerry and Holscher, Christian (2012) Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis. BMC Neuroscience, 13. pp. 33-38. ISSN 1471-2202
Jackson, Andrew P. and Berry, Andrew and Aslett, Martin and Allinson, Harriet C. and Burton, Peter and Vavrova-Anderson, Jana and Brown, Robert and Browne, Hilary and Corton, Nicola and Hauser, Heidi and Gamble, John and Gilderthorp, Ruth and Marcello, Lucio and McQuillan, Jacqueline and Otto, Thomas D. and Quail, Michael A. and Sanders, Mandy J. and van Tonder, Andries and Ginger, Michael and Field, Mark C. and Barry, J. David and Hertz-Fowler, Christiane and Berriman, Matthew (2012) Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species. Proceedings of the National Academy of Sciences, 109 (9). pp. 3416-3421. ISSN 0027-8424
Kasai, Takashi and Tokuda, Takahiko and Taylor, Mark and Nakagawa, Masanori and Allsop, David (2012) Utilization of a multiple antigenic peptide as a calibration standard in the BAN50 single antibody sandwich ELISA for Aß oligomers. Biochemical and Biophysical Research Communications, 422 (3). pp. 375-380. ISSN 0006-291X
Koudounas, Sofocles and Green, Edward W. and Clancy, David (2012) Reliability and variability of sleep and activity as biomarkers of ageing in Drosophila. Biogerontology, 13 (5). pp. 489-499. ISSN 1389-5729
Krause, Sue Ann and Cundell, Michael J. and Poon, Pak P. and McGhie, Josephine and Johnston, Gerry C. and Price, Clive and Gray, Joseph V. (2012) Functional specialisation of yeast Rho1 GTP exchange factors. Journal of Cell Science, 125 (11). pp. 2721-2731.
Li, Lin and Zhang, Zhi-Feng and Hölscher, Christian and Gao, Chong and Jiang, Yuan-Hong and Liu, Yue-Ze (2012) (Val⁸) glucagon-like peptide-1 prevents tau hyperphosphorylation, impairment of spatial learning and ultra-structural cellular damage induced by streptozotocin in rat brains. European Journal of Pharmacology, 674 (2-3). pp. 280-286. ISSN 0014-2999
McAinsh, Martin and Short, Ellie and North, Kathryn and Roberts, Michael and Shirras, Alan and Hetherington, Alistair (2012) A stress-specific calcium signature regulating an ozone-responsive gene expression network in Arabidopsis. Plant Journal, 71 (6). 948–961. ISSN 0960-7412
McGovern, Stephen F. J. and Hunter, Kerry and Hölscher, Christian (2012) Effects of the glucagon-like polypeptide-1 analogue (Val8)GLP-1 on learning, progenitor cell proliferation and neurogenesis in the C57B/16 mouse brain. Brain Research, 1473. pp. 204-213. ISSN 0006-8993
Morris, James A and Harrison, Linda M and Lauder, Robert M and Telford, David R and Neary, Richard (2012) Low dose, early mucosal exposure will minimize the risk of microbial disease. Medical Hypotheses, 79 (5). pp. 630-634.
Nagy, Olga and Pal, Margit and Udvardy, Andor and Shirras, Christine A. M. and Boros, Imre and Shirras, Alan D. and Deak, Peter (2012) lemmingA encodes the Apc11 subunit of the APC/C in Drosophila melanogaster that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2. Cell Division, 7 (n/a). ISSN 1747-1028
Parr-Sturgess, Catherine A. and Tinker, Claire L. and Hart, Claire A. and Brown, Michael D. and Clarke, Noel W. and Parkin, Edward T. (2012) Copper modulates zinc metalloproteinase-dependent ectodomain shedding of key signalling and adhesion proteins and promotes the invasion of prostate cancer epithelial cells. Molecular cancer research : MCR, 10 (10). pp. 1282-1293. ISSN 1557-3125
Popplewell, Jonathan and Swann, Marcus and Brown, Gavin and Lauder, Bob (2012) Fabrication of carbohydrate surfaces by using non-derivatised oligosaccharides. Methods in Molecular Biology, 808. pp. 221-229. ISSN 1940-6029
Pratt, Judith and Winchester, Catherine and Dawson, Neil and Morris, Brian (2012) Advancing schizophrenia drug discovery:optimizing rodent models to bridge the translational gap. Nature Reviews Drug Discovery, 11. pp. 560-579.
Rhodes, Glenn and Porter, Jonathon and Pickup, Roger (2012) The bacteriology of Windermere and its catchments:insights from 70 years of study. Freshwater Biology, 57 (2). pp. 305-320. ISSN 0046-5070
Roberts, Stephen and McAinsh, Martin and Widdicks, Lisa (2012) Cch1p mediates Ca2+ influx to protect Saccharomyces cerevisiae against eugenol toxicity. PloS ONE, 7 (9).
Robinson, M. and Domingues, P. and Gatherer, Derek and Mills, P. and Patel, A. and McLauchlan, J. (2012) Identification of genes that are differentially regulated during chronic hepatitis C virus infection of the liver using RNA-Seq. Immunology, 137 (Suppl.). p. 117. ISSN 0019-2805
Sant'anna, Mauricio R V and Darby, Alistair C and Brazil, Reginaldo P and Montoya-Lerma, James and Dillon, Viv M and Bates, Paul A and Dillon, Rod J (2012) Investigation of the bacterial communities associated with females of Lutzomyia sand fly species from South America. PloS ONE, 7 (8). e42531.
Sünram-Lea, Sandra-Ilona and Owen-Lynch, Jane and Robinson, Sarita J. and Jones, Emma and Hu, Henglong (2012) The effect of energy drinks on cortisol levels, cognition and mood during a fire-fighting exercise. Psychopharmacology, 219 (1). pp. 83-97. ISSN 0033-3158
Telleria, Erich L and Sant'Anna, Maurício R V and Ortigão-Farias, João R and Pitaluga, André N and Dillon, Viv M and Bates, Paul A and Traub-Csekö, Yara M and Dillon, Rod J (2012) Caspar-like gene depletion reduces Leishmania infection in sand fly host Lutzomyia longipalpis. Journal of Biological Chemistry, 287 (16). pp. 12985-12993. ISSN 0021-9258
Thurman, Jill and Parry, Jacqueline and Hill, Phil and Priscu, John and Vick, Trista and Chiuchiolo, Amy and Laybourn-Parry, Johanna (2012) Microbial dynamics and flagellate grazing during transition to winter in Lakes Hoare and Bonney, Antarctica. FEMS Microbiology Ecology, 82 (2). pp. 449-458. ISSN 0168-6496
Urbaniak, Michael and Guther, M. Lucia S. and Ferguson, Michael A. J. (2012) Comparative SILAC proteomic analysis of Trypanosoma brucei bloodstream and procyclic lifecycle stages. PLoS ONE, 7 (5). ISSN 1932-6203
Urbaniak, Michael D. and Mathieson, Toby and Bantscheff, Marcus and Eberhard, Dirk and Grimaldi, Raffaella and Miranda-Saavedra, Diego and Wyatt, Paul and Ferguson, Michael A. J. and Frearson, Julie and Drewes, Gerard (2012) Chemical proteomic analysis reveals the drugability of the kinome of Trypanosoma brucei. ACS Chemical Biology, 7 (11). pp. 1858-1865. ISSN 1554-8929
Vanni, Emilia and Gatherer, Derek and Tong, Lily and Everett, Roger D. and Boutell, Chris (2012) Functional characterization of residues required for the herpes simplex virus 1 E3 ubiquitin ligase ICP0 to interact with the cellular E2 ubiquitin-conjugating enzyme UBE2D1 (UbcH5a). Journal of Virology, 86 (11). pp. 6323-6333. ISSN 0022-538X
van Beurden, Steven J. and Gatherer, Derek and Kerr, Karen and Galbraith, Julie and Herzyk, Pawel and Peeters, Ben P. H. and Engelsma, Marc Y. and Rottier, Peter J. M. and Davison, Andrew J. (2012) Anguillid herpesvirus 1 transcriptome. Journal of Virology, 86 (18). pp. 10150-10161. ISSN 0022-538X