Nutritional Immunology: A Multi-Dimensional Approach

Ponton, Fleur and Wilson, Kenneth and Cotter, Sheena C. and Raubenheimer, David and Simpson, Stephen J. (2011) Nutritional Immunology: A Multi-Dimensional Approach. PLoS Pathogens, 7 (12). -. ISSN 1553-7374

Full text not available from this repository.

Abstract

Nutrition is critical to immune defence and resistance to pathogens, with consequences that affect the health, welfare, and reproductive success of individual organisms [1], [2], and also has profound ecological and evolutionary implications [3]–[5]. In humans, under-nutrition, notably of protein, is a major contributor to morbidity and mortality due to infectious diseases, particularly in the developing world [1]. Likewise, over-nutrition and its associated metabolic disorders may impair immune function, disrupt the relationship with symbiotic and commensal microbiota, and increase susceptibility to infectious disease [6]. Despite the undoubted importance of nutrition to immune defence, the challenge remains to capture the complexity of this relationship. There are three main aspects to this complexity: (i) nutrition is a complex multi-dimensional problem for hosts, pathogens, and commensals; (ii) host immunity is a complex, multi-dimensional trait; and (iii) nutrition and immunity interact via multiple direct and indirect pathways, including involvement of the host's microbiota.

Item Type:
Journal Article
Journal or Publication Title:
PLoS Pathogens
Uncontrolled Keywords:
/dk/atira/pure/subjectarea/asjc/2400/2405
Subjects:
?? LARVAL HELIOTHIS-VIRESCENSECOLOGICAL IMMUNOLOGYIMMUNE-SYSTEMSELENIUM SUPPLEMENTATIONEVOLUTIONARY ECOLOGYFEEDING-BEHAVIORINNATE IMMUNITYGUT MICROBIOMEPROTEIN COSTSTRADE-OFFSENVIRONMENTAL SCIENCEIMMUNOLOGYGENETICSVIROLOGYMOLECULAR BIOLOGYMICROBIOLOGYPARASIT ??
ID Code:
53496
Deposited By:
Deposited On:
13 Apr 2012 11:14
Refereed?:
Yes
Published?:
Published
Last Modified:
15 Sep 2023 00:00