Winzer, Klaus and Sun, Yao-hui and Green, Andrew and Delory, Marie and Blackley, David and Hardie, Kim R. and Baldwin, Thomas J. and Tang, Christoph M. (2002) Role of Neisseria meningitidis luxS in Cell-to-Cell Signaling and Bacteremic Infection. Infection and Immunity, 70 (4). pp. 2245-2248. ISSN 0019-9567Full text not available from this repository.
Numerous pathogenic bacteria contain luxS, which is required for autoinducer-2 production. Here, we demonstrate that Neisseria meningitidis contains a functional copy of luxS that is necessary for full meningococcal virulence; strains with a luxS deletion are defective for bacteremia, a prerequisite of meningococcal pathogenesis.
|Journal or Publication Title:||Infection and Immunity|
|Subjects:||Q Science > QH Natural history > QH301 Biology|
|Departments:||Faculty of Health and Medicine > Biomedical & Life Sciences|
|Deposited By:||Dr Klaus Winzer|
|Deposited On:||13 Jun 2008 14:15|
|Last Modified:||09 Dec 2016 02:14|
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