Winzer, Klaus and Sun, Yao-hui and Green, Andrew and Delory, Marie and Blackley, David and Hardie, Kim R. and Baldwin, Thomas J. and Tang, Christoph M. (2002) Role of Neisseria meningitidis luxS in Cell-to-Cell Signaling and Bacteremic Infection. Infection and Immunity, 70 (4). pp. 2245-2248. ISSN 0019-9567
Full text not available from this repository.Official URL: http://dx.doi.org/10.1128/IAI.70.4.2245-2248.2002
Abstract
Numerous pathogenic bacteria contain luxS, which is required for autoinducer-2 production. Here, we demonstrate that Neisseria meningitidis contains a functional copy of luxS that is necessary for full meningococcal virulence; strains with a luxS deletion are defective for bacteremia, a prerequisite of meningococcal pathogenesis.
| Item Type: | Article |
|---|---|
| Journal or Publication Title: | Infection and Immunity |
| Subjects: | Q Science > QH Natural history > QH301 Biology |
| Departments: | Faculty of Health and Medicine > Biomedical & Life Sciences |
| ID Code: | 9551 |
| Deposited By: | Dr Klaus Winzer |
| Deposited On: | 13 Jun 2008 14:15 |
| Refereed?: | Yes |
| Published?: | Published |
| Last Modified: | 26 Jul 2012 18:38 |
| Identification Number: | |
| URI: | http://eprints.lancs.ac.uk/id/eprint/9551 |
Actions (login required)
| View Item |
