Gibson, G. L. and Allsop, David and Austen, B. M. (2004) Induction of cellular oxidative stress by the β-amyloid peptide involved in Alzheimer's disease. Protein and Peptide Letters, 11 (3). pp. 257-270. ISSN 0929-8665Full text not available from this repository.
β-amyloid, the 39-43 amino acid peptide fragment originating from amyloid precursor protein, is today, generally accepted as the biological entity responsible for causing the debilitating human disorder Alzheimer's disease. Understanding the exact biological effects of β-amyloid in vitro and in vivo is clearly important to provide therapeutic strategies for the disease. Recent in vitro studies have focused on the production of reactive oxygen species by aggregating β- amyloid, but the cellular effects of β-amyloid induced reactive oxygen species production have not been fully elucidated.
|Journal or Publication Title:||Protein and Peptide Letters|
|Subjects:||Q Science > QH Natural history > QH301 Biology|
|Departments:||Faculty of Science and Technology > Lancaster Environment Centre|
Faculty of Health and Medicine > Biomedical & Life Sciences
|Deposited By:||Prof David Allsop|
|Deposited On:||15 May 2008 14:06|
|Last Modified:||01 Jan 2017 00:03|
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