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Photodynamic therapy and the alimentary tract.

Selvasekar, C. R. and Birbeck, N. and McMillan, Trevor J. and Wainwright, M. and Walker, S. J. (2001) Photodynamic therapy and the alimentary tract. Alimentary Pharmacology and Therapeutics, 15 (7). pp. 899-915. ISSN 0269-2813

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Abstract

Photodynamic therapy offers the possibility of relatively selective tumour necrosis and normal tissue healing. It has many potential applications but as yet no clear role. Articles, editorials and case reports published primarily in English and listed in Medline/ISI up to April 2000 or identified by a manual search have been reviewed in an attempt to provide a comprehensive overview of the use of photodynamic therapy in the alimentary tract. It is concluded that photodynamic therapy can be an effective treatment for superficial pre-malignant mucosal lesions and early cancers, especially in diffuse disease. Suitable patients include those wishing to avoid surgery, high risk subjects or those in whom other forms of treatment have failed. Superiority over other methods of ablation has not so far been demonstrated. Cheaper and more effective photosensitizers and improved techniques of light delivery are likely to increase the application of photodynamic therapy.

Item Type: Article
Journal or Publication Title: Alimentary Pharmacology and Therapeutics
Subjects: Q Science > QH Natural history > QH301 Biology
Departments: Faculty of Science and Technology > Lancaster Environment Centre
VC's Office
ID Code: 8725
Deposited By: Professor Trevor McMillan
Deposited On: 09 May 2008 10:15
Refereed?: Yes
Published?: Published
Last Modified: 09 Apr 2014 22:13
Identification Number:
URI: http://eprints.lancs.ac.uk/id/eprint/8725

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