Synthesis and substrate-controlled reactions of 2,2′-Unsaturated biquinazolinones

Pertusati, Fabrizio and Nutz, Eva and Kariuki, Benson M. and Coogan, Michael Peter (2017) Synthesis and substrate-controlled reactions of 2,2′-Unsaturated biquinazolinones. Tetrahedron, 73 (1). pp. 55-63. ISSN 0040-4020

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Official URL: https://doi.org/10.1016/j.tet.2016.11.060

Abstract

A series of BiQuinazolinones bearing either double or triple bonds in their lateral chains have been synthesized. These compounds were then subjected to substrate-controlled reactions such as Diels-Alder, epoxidation and Pauson-Khand reactions. The stereoselective outcome observed in these transformations is very promising for the future application of BiQuinazolinones as chiral auxiliaries.

Item Type:

Journal Article

Journal or Publication Title:

Tetrahedron

Additional Information:

This is the author’s version of a work that was accepted for publication in Tetrahedron. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Tetrahedron, 73, 1, 2016 DOI: 10.1016/j.tet.2016.11.060

Uncontrolled Keywords:

/dk/atira/pure/subjectarea/asjc/3000/3002

Subjects:

?? BIQUINAZOLINONEATROPISOMERSDIASTEREOSELECTIVITYCHIRAL INDUCTIONBIOCHEMISTRYORGANIC CHEMISTRYDRUG DISCOVERY ??

ID Code:

83136

Deposited By:

ep_importer_pure

Deposited On:

24 Nov 2016 10:02

Refereed?:

Yes

Published?:

Published

Last Modified:

20 Sep 2023 00:58

URI:

https://eprints.lancs.ac.uk/id/eprint/83136