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Perfect Simulation From Nonneutral Population Genetic Models: Variable Population Size and Population Subdivision.

Fearnhead, Paul (2006) Perfect Simulation From Nonneutral Population Genetic Models: Variable Population Size and Population Subdivision. Genetics, 174. pp. 1397-1406.

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    Abstract

    We show how the idea of monotone coupling from the past can produce simple algorithms for simulating samples at a nonneutral locus under a range of demographic models. We specifically consider a biallelic locus and either a general variable population size mode or a general migration model for population subdivision. We investigate the effect of demography on the efficacy of selection and the effect of selection on genetic divergence between populations.

    Item Type: Article
    Journal or Publication Title: Genetics
    Subjects: Q Science > QA Mathematics
    Departments: Faculty of Science and Technology > Mathematics and Statistics
    ID Code: 8187
    Deposited By: Prof Paul Fearnhead
    Deposited On: 15 Apr 2008 11:23
    Refereed?: Yes
    Published?: Published
    Last Modified: 09 Oct 2013 15:41
    Identification Number:
    URI: http://eprints.lancs.ac.uk/id/eprint/8187

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