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The psychosocial impact of human papillomavirus testing in primary cervical screening—a study within a randomized trial

Kitchener, Henry C. and Fletcher, Ian and Roberts, C and Wheeler, P and Almonte, M and Maguire, P (2008) The psychosocial impact of human papillomavirus testing in primary cervical screening—a study within a randomized trial. International Journal of Gynecological Cancer, 18 (4). pp. 743-748. ISSN 1048-891X

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Abstract

The purpose of the study was to assess the psychosocial impact of human papillomavirus (HPV) testing as an adjunct to cytology in routine primary cervical screening. A controlled study of the psychosocial impact of HPV testing within a randomized trial of HPV testing to assess its efficacy in cervical screening was carried out. The trial provides a randomized setting of revealed HPV results versus concealed results permitting valid comparisons for assessing true psychosocial impact. The setting comprised a large number of general practices in primary care. Women aged 20–64 years who underwent routine cervical screening participated in the study. The intervention was a revealed high-risk HPV test result in addition to cervical cytology. The main outcome was measured using General Health Questionnaire (GHQ-28), Spielberger State–Trait Anxiety Inventory, and Sexual Rating Scale (SRS). Among women with either mildly abnormal or normal cytology, receiving an HPV(+ve) result did not impact significantly on GHQ caseness and mean scores or on Spielberger State and Trait scores when compared with women in whom the HPV(+ve) test result was concealed. Among women with normal cytology, receiving an HPV(+ve) result was associated with a reduction in the Sexual Rating Scale compared with similar women whose HPV(+ve) result was concealed. HPV testing does not add significant psychologic distress when combined with cytology in routine primary cervical screening.

Item Type: Article
Journal or Publication Title: International Journal of Gynecological Cancer
Uncontrolled Keywords: cervical screening ; HPV ; psychologic
Subjects: R Medicine > R Medicine (General)
Departments: Faculty of Health and Medicine > Health Research
ID Code: 58643
Deposited By: ep_importer_pure
Deposited On: 01 Oct 2012 10:19
Refereed?: Yes
Published?: Published
Last Modified: 01 Oct 2012 10:19
Identification Number:
URI: http://eprints.lancs.ac.uk/id/eprint/58643

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