Lueck, C. J. and Tanyeri, S. and Kennard, C. and Crawford, Trevor and Henderson, L. (1992) Saccadic Eye Movements in Parkinson's Disease: I. Delayed Saccades. Quarterly Journal of Experimental Psychology Series a Human Experimental Psychology, 45 (2). pp. 193-210. ISSN 0272-4987Full text not available from this repository.
The saccadic eye movements of nine patients with Parkinson’s disease were compared to those of nine age-matched controls in two paradigms generating volitional saccades. In both paradigms. subjects had to make delayed saccades to peripheral LED targets: a peripheral target appeared 700 msec before a buzzer sounded, the buzzer being the signal to make a saccade to the target. In the first paradigm (“centre-off“), the fixation target was extinguished simultaneously with buzzer onset. In the second (“centreremain”) it was not extinguished until 1000 msec later. The results showed that for outward saccades in both paradigms, there was no difference between Parkinsonian patients and controls, but saccadic latencies were significantly shorter in the “centre-remain” paradigm. The initial outward saccades were indistinguishable from the normal, reflex saccades of the same subjects. However, saccades returning to the centre (a type of remembered target saccade) were hypometric and showed multistepping. Both effects were more pronounced in patients with Parkinson’s disease. The significance of these findings in terms of current hypotheses about the nature of the Parkinsonian saccadic deficit is discussed.
|Journal or Publication Title:||Quarterly Journal of Experimental Psychology Series a Human Experimental Psychology|
|Uncontrolled Keywords:||Saccade ; Parkinson's disease|
|Subjects:||B Philosophy. Psychology. Religion > BF Psychology|
|Departments:||Faculty of Science and Technology > Psychology|
|Deposited On:||16 Oct 2012 14:50|
|Last Modified:||07 Jan 2015 17:53|
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