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The toxic effect of Streptomyces griseus spores and exudates on gill pathology of freshwater fish

Lewis, J. W. and Morley, N.J. and Drinkall, Janice and Jamieson, B. J. and Wright, R. and Parry, Jacqueline (2009) The toxic effect of Streptomyces griseus spores and exudates on gill pathology of freshwater fish. Ecotoxicology and Environmental Safety, 72 (1). pp. 173-181. ISSN 0147-6513

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Many unexplained fish-kills in British waters are considered microbial in origin and a large proportion of field sites contains elevated concentrations of filamentous actinobacteria. The present study has shown that a strain of Streptomycesgriseus, isolated from field sites, elicits pathological changes to the gills of fish under laboratory conditions which mirror those found in situ. These changes include hyperplasia leading to fusion of the secondary lamellae and loss of microridging on the filamental epithelium of the primary lamellae. Juveniles of up to six fish species were exposed to spore suspensions or exudate of S. griseus in the range of 1×102–1×106 spores ml−1 for up to 96 h. The exudate was more potent than the spores and there was a positive correlation between exudate concentration and the rate and extent of fish gill pathology with bream and rainbow trout being more sensitive than carp, tench and roach. The results are discussed in the context of recognising and managing potential fish mortalities caused by microbial toxins.

Item Type: Journal Article
Journal or Publication Title: Ecotoxicology and Environmental Safety
Uncontrolled Keywords: Actinobacteria ; Exotoxin ; Streptomyces ; Lamellae ; Epithelia ; Hyperplasia
Subjects: ?? qr ??
Departments: Faculty of Health and Medicine > Biomedical & Life Sciences
ID Code: 55964
Deposited By: ep_importer_pure
Deposited On: 19 Jul 2012 16:40
Refereed?: Yes
Published?: Published
Last Modified: 26 Apr 2018 03:58
Identification Number:

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