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The isolation and amino acid composition of senile plaque core protein

Allsop, D and Landon, M and Kidd, M (1983) The isolation and amino acid composition of senile plaque core protein. Experimental Brain Research, 259 (2). pp. 348-52. ISSN 0014-4819

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Abstract

A new method has been developed for the isolation of intact senile (neuritic) plaque cores from post-mortem brains of patients with Alzheimer's disease. The plaque cores were found to be insoluble in various protein denaturants. The amino acid composition of the plaque core protein does not resemble that of any known form of amyloid.

Item Type: Article
Journal or Publication Title: Experimental Brain Research
Uncontrolled Keywords: Aged ; Alzheimer Disease ; Amino Acids ; Amyloid ; Cerebral Cortex ; Dementia ; Humans ; Middle Aged ; Nerve Tissue Proteins ; Neurofibrils ; Neurons
Subjects:
Departments: Faculty of Health and Medicine > Biomedical & Life Sciences
ID Code: 50875
Deposited By: ep_importer_pure
Deposited On: 01 Nov 2011 16:18
Refereed?: Yes
Published?: Published
Last Modified: 26 Jul 2012 19:44
Identification Number:
URI: http://eprints.lancs.ac.uk/id/eprint/50875

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