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Enhanced relapse prevention for bipolar disorder by community mental health teams:cluster feasibility randomised trial

Lobban, F. and Taylor, L. and Chandler, C. and Tyler, E. and Kinderman, P. and Kolamunnage-Dona, R. and Gamble, C. and Peters, S. and Pontin, E. and Sellwood, W. and Morriss, R. K. (2010) Enhanced relapse prevention for bipolar disorder by community mental health teams:cluster feasibility randomised trial. British Journal of Psychiatry, 196 (1). pp. 59-63. ISSN 1472-1465

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Abstract

Background Relapse prevention for bipolar disorder increases time to relapse but is not available in routine practice. Aims To determine the feasibility and effectiveness of training community mental health teams (CMHTS) to deliver enhanced relapse prevention. Method in a cluster randomised controlled trial, CMHT workers were allocated to receive 12h training in enhanced relapse prevention to offer to people with bipolar disorder or to continue giving treatment as usual. The primary outcome was time to relapse and the secondary outcome was functioning. Results Twenty-three CMHTs and 96 service users took part. Compared with treatment as usual, enhanced relapse prevention increased median time to the next bipolar episode by 8.5 weeks (hazard ratio 0.79, 95% CI 0.45-1.38). Social and occupational functioning improved with the intervention (regression coefficient 0.68, 95% CI 0.05-1.32). The clustering effect was negligible but imprecise (intracluster correlation coefficient 0.0001, 95% CI 0.0000-0.5142). Conclusions Training care coordinators to offer enhanced relapse prevention for bipolar disorder may be a feasible effective treatment. Large-scale cluster trials are needed.

Item Type: Article
Journal or Publication Title: British Journal of Psychiatry
Uncontrolled Keywords: GROUP PSYCHOEDUCATION ; CARE ; IMPAIRMENT ; SYMPTOMS ; EFFICACY
Subjects: UNSPECIFIED
Departments: UNSPECIFIED
ID Code: 49353
Deposited By: ep_importer_pure
Deposited On: 24 Aug 2011 11:52
Refereed?: Yes
Published?: Published
Last Modified: 23 Jul 2014 14:54
Identification Number:
URI: http://eprints.lancs.ac.uk/id/eprint/49353

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