NANAEV, A K and RUKOSUEV, V S and SHIRINSKY, V P and MILOVANOV, A P and DOMOGATSKY, S P and DUANCE, V C and BRADBURY, F M and YARROW, P and GARDINER, L and DLACEY, C and OCKLEFORD, C D (1991) CONFOCAL AND CONVENTIONAL IMMUNOFLUORESCENT AND IMMUNOGOLD ELECTRON-MICROSCOPIC LOCALIZATION OF COLLAGEN TYPE-III AND TYPE-IV IN HUMAN PLACENTA. Placenta, 12 (6). pp. 573-595. ISSN 0143-4004Full text not available from this repository.
Confocal and conventional indirect immunofluorescence and immunogold electron microscopic methods were applied to examine the distribution of extracellular matrix constituents (collagens types III and ITq in the villi of immature and term human placentae. The immunofluorescence study revealed that collagen type III is more distinct in the villous stroma of terns placenta as compared with that of the first trimester. Collagen type IV was detected mainly in endothelial and epithelial basement membranes and interestingly also to a certain extent in the stroma. Results obtained using immunoelectron microscopy support the proposal that collagen types III and IV are characteristic of stromal and basement membranes, respectively. Stromal collagen type IV is apparently localized in association with the interstitial types of collagen (I and III), in the villous stroma of term placenta.
|Journal or Publication Title:||Placenta|
|Uncontrolled Keywords:||BASEMENT-MEMBRANE COMPONENTS ; EXTRACELLULAR-MATRIX ; CHORIONIC VILLI ; MESSENGER-RNA ; LYMPH-NODE ; PROTEINS ; LAMININ ; IDENTIFICATION ; ULTRASTRUCTURE ; FIBRONECTIN|
|Departments:||Faculty of Health and Medicine > Medicine|
|Deposited On:||24 Aug 2011 10:06|
|Last Modified:||09 Feb 2016 01:08|
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