Lancaster EPrints

THE MODE OF INSERTION OF UMBILICAL-CORD AND VESSELS - ASSOCIATION WITH MATERNAL HEMOGLOBIN GENOTYPE, NEONATAL FACTORS, AND PLACENTAL COMPONENT VOLUMES

ADDAI, F K and QUASHIE, F J K and OCKLEFORD, C D (1994) THE MODE OF INSERTION OF UMBILICAL-CORD AND VESSELS - ASSOCIATION WITH MATERNAL HEMOGLOBIN GENOTYPE, NEONATAL FACTORS, AND PLACENTAL COMPONENT VOLUMES. Anatomy and Embryology, 189 (2). pp. 107-114. ISSN 0340-2061

Full text not available from this repository.

Abstract

We investigated whether variations in mode of attachment of umbilical cords and vessels coincided with differences in maternal haemoglobin genotype and neonatal factors or placental micro-volumetric composition. The incidence of placentae with marginally inserted cords, or those in which umbilical vessels separated prior to insertion, was not statistically different in samples from sickle cell patients having haemoglobin-SS and haemoglobin-SC genotypes, as compared with haemoglobin-AA controls. Results obtained from analysis of variance (ANOVA) suggest that the mode of insertion (status) of umbilical vessels may have clinical significance, because it produced differences in the main effects associated with neonatal gestational age, placental weight, and placental index. Point counting stereology was employed to estimate the microscopic compartment volumes of placentae prior to an assessment of statistical association between the data obtained and the status of umbilical vessels and maternal haemoglobin genotype. Furcate placentae (with separated umbilical vessels) had statistically greater than normal volumes of villi, villous trophoblast, and syncytial knots. We deduce that furcate placentae are prone to early delivery, because they are heavier, having more voluminous villi with more trophoblast and syncytial knots than controls.

Item Type: Article
Journal or Publication Title: Anatomy and Embryology
Uncontrolled Keywords: PLACENTA ; UMBILICAL CORD ; VOLUMETRIC COMPOSITION
Subjects:
Departments: Faculty of Health and Medicine > Medicine
ID Code: 49259
Deposited By: ep_importer_pure
Deposited On: 04 Aug 2011 14:00
Refereed?: Yes
Published?: Published
Last Modified: 26 Jul 2012 19:26
Identification Number:
URI: http://eprints.lancs.ac.uk/id/eprint/49259

Actions (login required)

View Item