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Paclitaxel (Taxol®) — a guide to administration (Nursing Implications of introducing a new chemotherapeutic agent)

Preston, Nancy (1996) Paclitaxel (Taxol®) — a guide to administration (Nursing Implications of introducing a new chemotherapeutic agent). European Journal of Cancer Care, 5 (3). pp. 147-152.

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Abstract

The introduction of a new chemotherapeutic agent has implications for nursing care. Paclitaxel (Taxol®) chemotherapy is now being used throughout Europe for treatment of patients with ovarian cancer who have previously failed a platinum-containing chemotherapy regimen, and in many countries to treat metastatic breast cancer. Nurses need to be equipped to care for these patients receiving Paclitaxel. This paper introduces nurses to Paclitaxel, the history of its development, its mechanism of action, potential side-effects and administration. Paclitaxel's side-effects include hypersensitivity reactions, neutropaenia, peripheral neuropathy, asymptomatic bradycardia, alopecia, malaise, myalgias and arthralgias. Administration guidelines will be discussed because Paclitaxel leaches plasticizer from polyvinyl chloride (PVC) intravenous-giving sets normally used to administer chemotherapy, hence an alternative delivery system is required.

Item Type: Article
Journal or Publication Title: European Journal of Cancer Care
Subjects: R Medicine > R Medicine (General)
Departments: Faculty of Health and Medicine > Health Research
ID Code: 32417
Deposited By: Mrs Yaling Zhang
Deposited On: 25 Mar 2010 10:08
Refereed?: Yes
Published?: Published
Last Modified: 26 Jul 2012 17:10
Identification Number:
URI: http://eprints.lancs.ac.uk/id/eprint/32417

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