Kierkegaard, Amelie and Asplund, Lillemor and de Wit, Cynthia A. and McLachlan, Michael S. and Thomas, Gareth O. and Sweetman, Andrew J. and Jones, Kevin C. (2007) Fate of higher brominated PBDEs in lactating cows. Environmental Science and Technology, 41 (2). pp. 417-423. ISSN 0013-936XFull text not available from this repository.
Dietary intake studies of lower brominated diphenyl ethers (BDEs) have shown that fish and animal products are important vectors of human exposure, but almost no data exist for higher brominated BDEs. Therefore, the fate of hepta- to decaBDEs was studied in lactating cows exposed to a naturally contaminated diet by analyzing feed, feces, and milk samples from a previous mass balance study of PCB. Tissue distribution was studied in one cow slaughtered after the experiment. BDE-209 was the dominant congener in feed, organs, adipose tissues, and feces, but not in milk. In contrast to PCBs and lower brominated BDEs, concentrations of hepta- to decaBDEs in adipose tissue were 9−80 times higher than in milk fat and the difference increased with degree of bromination/log Kow. The congener profiles in adipose tissue and feed differed; BDE-207, BDE-196, BDE-197, and BDE-182 accumulated to a surprisingly greater extent in the fat compared to their isomers, suggesting metabolic debromination of BDE-209 to these BDEs. The results indicate that meat rather than dairy product consumption may be an important human exposure route to higher brominated BDEs.
|Journal or Publication Title:||Environmental Science and Technology|
|Subjects:||?? ge ??|
|Departments:||Faculty of Science and Technology > Lancaster Environment Centre|
|Deposited By:||Mr Richard Ingham|
|Deposited On:||30 Oct 2009 16:27|
|Last Modified:||23 Mar 2017 17:28|
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