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Statistical issues in the assessment of health outcomes in children : methodological review.

Lancaster, Gillian (2009) Statistical issues in the assessment of health outcomes in children : methodological review. Journal of the Royal Statistical Society: Series A (Statistics in Society), 172 (4). pp. 707-727. ISSN 1467-985X

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    Abstract

    The lack of outcome measures that are validated for use on children limits the effectiveness and generalizability of paediatric health care interventions. Statistical epidemiology is a broad concept encompassing a wide range of useful techniques for use in child health outcome assessment and development. However, the range of techniques that are available is often confusing and prohibits their adoption. In the paper an overview of methodology is provided within the paediatric context. It is demonstrated that in many cases assessment can be performed relatively straightforwardly by using standard statistical techniques, although sometimes more sophisticated techniques are required. Examples of both physiological and questionnaire-based outcomes are given. The usefulness of these techniques is highlighted for achieving specific objectives and ultimately for achieving methodological rigour in clinical outcome studies that are performed in the paediatric population.

    Item Type: Article
    Journal or Publication Title: Journal of the Royal Statistical Society: Series A (Statistics in Society)
    Additional Information: This is a pre-print of an article published in Journal of the Royal Statistical Society: Series A (Statistics in Society), 172 (4), 2009. (c) Wiley.
    Uncontrolled Keywords: Child health ; PROMs ; Child mental health ; Health outcomes ; Quality of life ; Statistical methodology ; Study design
    Subjects: Q Science > QA Mathematics
    Departments: Faculty of Science and Technology > Mathematics and Statistics
    ID Code: 26964
    Deposited By: Mr Richard Ingham
    Deposited On: 19 Aug 2009 13:34
    Refereed?: Yes
    Published?: Published
    Last Modified: 06 Aug 2014 10:58
    Identification Number:
    URI: http://eprints.lancs.ac.uk/id/eprint/26964

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