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Atomic force microscopy of the cornea and sclera.

Fullwood, N. J. and Hammiche, A. and Pollock, H. M. and Hourston, D. J. and Song, M. (1995) Atomic force microscopy of the cornea and sclera. Current Eye Research, 14 (7). pp. 529-535.

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Abstract

We report the first investigation of the extracellular matrix of cornea and sclera using an atomic force microscope (AFM), and evaluate the potential of this new technique. We were able to obtain 2-3 nanometre resolution of both tissues in a condition close to their native state. The AFM was able to resolve surface features on the collagen fibrils, as well as providing unique images of crossbridge structures between collagen fibrils in both cornea and sclera.

Item Type: Article
Journal or Publication Title: Current Eye Research
Uncontrolled Keywords: atomic force microscope ; cornea ; sclera ; extracellular matrix
Subjects: G Geography. Anthropology. Recreation > GE Environmental Sciences
Departments: Faculty of Health and Medicine > Biomedical & Life Sciences
Faculty of Science and Technology > Physics
ID Code: 22263
Deposited By: ep_ss_importer
Deposited On: 10 Feb 2009 11:32
Refereed?: No
Published?: Published
Last Modified: 26 Jul 2012 15:58
Identification Number:
URI: http://eprints.lancs.ac.uk/id/eprint/22263

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