Ettinger, Ulrich and Kumari, Veena and Chitnis, Xavier A. and Corr, Philip J. and Sumich, Alex L. and Rabe-Hesketh, Sophia and Crawford, Trevor J. and Sharma, Tonmoy (2002) Relationship between brain structure and saccadic eye movements in healthy humans. Neuroscience Letters, 328 (3). pp. 225-228. ISSN 0304-3940Full text not available from this repository.
This study used structural magnetic resonance imaging (MRI) to investigate associations between brain structure and saccadic eye movements. Seventeen healthy subjects underwent structural MRI and infra-red oculographic assessment of a reflexive saccade task. Volumes of prefrontal, premotor, and occipitoparietal cortex, caudate, thalamus, and cerebellar vermis were used as predictors in multiple regression with prosaccade gain as a dependent variable, controlling for whole-brain volume. Using voxel-based morphometry (VBM), gain was entered into correlational analysis with grey matter density. Regression analysis indicated that vermis volumes predicted prosaccade gain. VBM replicated this finding: gain was correlated with grey matter in the left cerebellar hemisphere and vermis. These findings agree with previous studies on the role of the cerebellar vermis in saccadic gain and support the validity of structural neuroimaging methods in elucidating the neural correlates of saccadic eye movements.
|Journal or Publication Title:||Neuroscience Letters|
|Uncontrolled Keywords:||Structural magnetic resonance imaging ; Voxel-based morphometry ; Prosaccade (reflexive saccade) ; Cerebellar vermis ; Human|
|Subjects:||B Philosophy. Psychology. Religion > BF Psychology|
|Departments:||Faculty of Science and Technology > Psychology|
|Deposited By:||Dr Trevor Crawford|
|Deposited On:||04 Aug 2008 11:33|
|Last Modified:||07 Jan 2015 12:45|
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