Wright, T. J. and Huddart, H. (1999) Electrophysiological and pharmacological characteristics of buccal smooth muscle of the pest slug Deroceras reticulatum. Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology, 169 (8). pp. 561-568. ISSN 0174-1578Full text not available from this repository.
Buccal mass muscle of the pest slug Deroceras reticulatum was examined by conventional tension recording and the sucrose-gap electrophysiological technique. Elevated potassium salines induced dose-dependent depolarisations accompanied by tonic contractures with superimposed rapid twitch contractions. The latter were suppressed at over 40 mmol · l−1 external potassium, where depolarisation-induced inactivation of voltage-sensitive calcium channels may have occurred. Acetylcholine caused significant dose-dependent depolarisations and tonic contractures, while 5-hydroxy tryptamine induced lower depolarisations accompanied by phasic contractile activity superimposed on low level tonic force. Of the purines examined only guanosine triphosphate caused significant mechanical activity above a threshold of 0.1 μmol · l−1. The tetrapeptides inhibited buccal muscle spontaneous activity, but the related small cardioactive peptide B was weakly excitatory. The amino acids glutamate and gamma-aminobutyric acid were weakly excitatory on buccal muscle while the molluscicides metaldehyde and methiocarb disrupted normal mechanical activity of the feeding musculature. Acetylcholine and 5-hydroxytryptamine appear to have major roles in regulating feeding muscle activity, seemingly modulated by guanosine triphosphate and inhibited by phenylalanine-methionine-arginine-phenylalanine-NH2 and phenylalanine-leucine-arginine-phenylalanine-NH2.
|Journal or Publication Title:||Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology|
|Uncontrolled Keywords:||Acetylcholine - Deroceras reticulatum - FMRFamide - FLRFamide - GTP 5-Hydroxytryptamine - Metaldehyde - Methiocarb - Sucrose Gap|
|Subjects:||Q Science > QH Natural history > QH301 Biology|
|Deposited By:||Mr Richard Ingham|
|Deposited On:||29 Jul 2008 10:14|
|Last Modified:||18 Sep 2013 16:02|
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