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Horizons in nutritional science : The case for strategic international alliances to harness nutritional genomics for public and personal health.

Chadwick, Ruth, et al. (2005) Horizons in nutritional science : The case for strategic international alliances to harness nutritional genomics for public and personal health. British Journal of Nutrition, 94 (5). pp. 623-632. ISSN 1475-2662

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    Abstract

    Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, and bioactive compounds. Results from molecular and genetic epidemiological studies indicate that dietary unbalance can alter gene–nutrient interactions in ways that increase the risk of developing chronic disease. The interplay of human genetic variation and environmental factors will make identifying causative genes and nutrients a formidable, but not intractable, challenge. We provide specific recommendations for how to best meet this challenge and discuss the need for new methodologies and the use of comprehensive analyses of nutrient–genotype interactions involving large and diverse populations. The objective of the present paper is to stimulate discourse and collaboration among nutrigenomic researchers and stakeholders, a process that will lead to an increase in global health and wellness by reducing health disparities in developed and developing countries.

    Item Type: Article
    Journal or Publication Title: British Journal of Nutrition
    Additional Information: http://journals.cambridge.org/action/displayJournal?jid=BJN The final, definitive version of this article has been published in the Journal, British Journal of Nutrition, 94 (5), pp 623-632 2005, © 2005 Cambridge University Press.
    Uncontrolled Keywords: Strategic international alliances ; Nutrigenomics ; Gene–nutrient interactions ; Health diaparities
    Subjects: B Philosophy. Psychology. Religion > B Philosophy (General)
    Departments: Faculty of Arts & Social Sciences > Politics & International Relations (Merged into PPR 2010-08-01)
    Faculty of Arts & Social Sciences > Sociology
    ID Code: 10810
    Deposited By: Mrs Yaling Zhang
    Deposited On: 24 Jul 2008 15:58
    Refereed?: Yes
    Published?: Published
    Last Modified: 18 Sep 2013 15:58
    Identification Number:
    URI: http://eprints.lancs.ac.uk/id/eprint/10810

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