Azevedo, R. A. and Lea, P. J. (2001) Lysine metabolism in higher plants. Amino Acids, 20 (3). pp. 261-279. ISSN 0939-4451
Full text not available from this repository.Abstract
The essential amino acid lysine is synthesised in higher plants via a pathway starting with aspartate, that also leads to the formation of threonine, methionine and isoleucine. Enzyme kinetic studies and the analysis of mutants and transgenic plants that overaccumulate lysine, have indicated that the major site of the regulation of lysine synthesis is at the enzyme dihydrodipicolinate synthase. Despite this tight regulation, there is strong evidence that lysine is also subject to catabolism in plants, specifically in the seed. The two enzymes involved in lysine breakdown, lysine 2-oxoglutarate reductase (also known as lysine α-ketoglutarate reductase) and saccharopine dehydrogenase exist as a single bifunctional protein, with the former activity being regulated by lysine availability, calcium and phosphorylation/dephosphorylation.
| Item Type: | Article |
|---|---|
| Journal or Publication Title: | Amino Acids |
| Uncontrolled Keywords: | Amino acids - Aspartate kinase - Aspartate - Lysine synthesis - Lysine 2-oxoglutarate reductase - Methionine - Threonine |
| Subjects: | Q Science > QH Natural history > QH301 Biology |
| Departments: | Faculty of Science and Technology > Lancaster Environment Centre |
| ID Code: | 10775 |
| Deposited By: | Mr Richard Ingham |
| Deposited On: | 24 Jul 2008 09:39 |
| Refereed?: | Yes |
| Published?: | Published |
| Last Modified: | 26 Jul 2012 14:53 |
| Identification Number: | |
| URI: | http://eprints.lancs.ac.uk/id/eprint/10775 |
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